RAEducation » morphine http://www.raeducation.com Regional Anesthesia Education...and Discussion Tue, 06 Apr 2010 12:21:26 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 Prolonged use of high-dose morphine impairs angiog…[Anesth Analg. 2008] – PubMed Result http://www.raeducation.com/2008/12/prolonged-use-of-high-dose-morphine-impairs-angioganesth-analg-2008-pubmed-result/ http://www.raeducation.com/2008/12/prolonged-use-of-high-dose-morphine-impairs-angioganesth-analg-2008-pubmed-result/#comments Tue, 30 Dec 2008 02:30:56 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=251 Yet Another Related Posts Plugin.]]> Very interesting.

Prolonged use of high-dose morphine impairs angiog…[Anesth Analg. 2008] – PubMed Result
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]]> http://www.raeducation.com/2008/12/prolonged-use-of-high-dose-morphine-impairs-angioganesth-analg-2008-pubmed-result/feed/ 0 Pre-treatment with morphine does not prevent the development of remifentanil-induced hyperalgesia. [Can J Anaesth. 2008] – PubMed Result http://www.raeducation.com/2008/12/pre-treatment-with-morphine-does-not-prevent-the-dcan-j-anaesth-2008-pubmed-result/ http://www.raeducation.com/2008/12/pre-treatment-with-morphine-does-not-prevent-the-dcan-j-anaesth-2008-pubmed-result/#comments Mon, 01 Dec 2008 11:49:46 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=216 Yet Another Related Posts Plugin.]]>
Pre-treatment with morphine does not prevent the development of remifentanil-induced hyperalgesia. [Can J Anaesth. 2008] – PubMed Result
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Interesting. This study took 2 groups of children undergoing scoliosis surgery under remifentanil, starting dose well within the usual range. One group received morphine (0.15mg/kg) prior to the remi, the other group saline. The group which received the morphine did NOT have decreased post-operative morphine requirements. Instead, this group trended towards increased requirements. All patients who were changed from morphine to hydromophone were also in the morphine group.

The discussion has a nice review of the topic, noting similar findings (or failure, rather) when fentanyl was used as the pretreating agent.

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