RAEducation » Pharmacology http://www.raeducation.com Regional Anesthesia Education...and Discussion Tue, 06 Apr 2010 12:21:26 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 Epidural Catheter Disconnects http://www.raeducation.com/2010/02/epidural-catheter-disconnects/ http://www.raeducation.com/2010/02/epidural-catheter-disconnects/#comments Fri, 26 Feb 2010 23:47:39 +0000 BlueNeedle http://www.raeducation.com/2010/02/epidural-catheter-disconnects/ Yet Another Related Posts Plugin.]]> A 74 year-old female with borderline renal function and a history of spinal stenosis has an epidural catheter in place. She is post-op day 2 from a colon surgery for cancer.

This morning, she was diagnosed with a PE, and was given 1mg/kg of enoxaparin. Six hours after the lovenox, the nurse calls the acute pain service. Apparently the epidural catheter has become disconnected in the last 3 hours (the disconnect was unwitnessed). The tips were found lying on the bed near the patient’s urinal.

How would you manage this situation?

No related posts.

Related posts brought to you by Yet Another Related Posts Plugin.

]]> http://www.raeducation.com/2010/02/epidural-catheter-disconnects/feed/ 2 A Brief History of the Placebo http://www.raeducation.com/2009/09/a-brief-history-of-the-placebo/ http://www.raeducation.com/2009/09/a-brief-history-of-the-placebo/#comments Wed, 09 Sep 2009 12:00:32 +0000 admin http://www.anest.ufl.edu/gator-rap/?p=905 Yet Another Related Posts Plugin.]]> Who knew that anesthesia had such an integral role in the modern placebo? A simply fantastic introduction to the topic, from a slightly uncharacteristic source.

No related posts.

Related posts brought to you by Yet Another Related Posts Plugin.

]]> http://www.raeducation.com/2009/09/a-brief-history-of-the-placebo/feed/ 0 Fentanyl and Morphine: A CV Editorial http://www.raeducation.com/2009/07/fentanyl-and-morphine-a-cv-editorial/ http://www.raeducation.com/2009/07/fentanyl-and-morphine-a-cv-editorial/#comments Mon, 27 Jul 2009 02:08:21 +0000 admin http://www.anest.ufl.edu/gator-rap/?p=874 Yet Another Related Posts Plugin.]]> It’s not too often that you’ll see us commenting on cardiac anesthetics. However, this editorial on the use of morphine and fentanyl in CV anesthesia summarizes some very nice points differentiating the two. Highly recommended, this is a short editorial worthy of your attention.

Ovid: External Link.

No related posts.

Related posts brought to you by Yet Another Related Posts Plugin.

]]> http://www.raeducation.com/2009/07/fentanyl-and-morphine-a-cv-editorial/feed/ 0 Vioxx maker Merck and Co drew up doctor hit list | The Australian http://www.raeducation.com/2009/04/vioxx-maker-merck-and-co-drew-up-doctor-hit-list-the-australian/ http://www.raeducation.com/2009/04/vioxx-maker-merck-and-co-drew-up-doctor-hit-list-the-australian/#comments Sat, 25 Apr 2009 21:55:01 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=476 Yet Another Related Posts Plugin.]]> Quite the shocking revelation.

From the article:

AN international drug company made a hit list of doctors who had to be “neutralised” or discredited because they criticised the anti-arthritis drug the pharmaceutical giant produced.

Staff at US company Merck &Co emailed each other about the list of doctors – mainly researchers and academics – who had been negative about the drug Vioxx or Merck and a recommended course of action.

The email, which came out in the Federal Court in Melbourne yesterday as part of a class action against the drug company, included the words “neutralise”, “neutralised” or “discredit” against some of the doctors’ names.

It is also alleged the company used intimidation tactics against critical researchers, including dropping hints it would stop funding to institutions and claims it interfered with academic appointments.

“We may need to seek them out and destroy them where they live,” a Merck employee wrote, according to an email excerpt read to the court by Julian Burnside QC, acting for the plaintiff.

Vioxx maker Merck and Co drew up doctor hit list | The Australian.

No related posts.

Related posts brought to you by Yet Another Related Posts Plugin.

]]> http://www.raeducation.com/2009/04/vioxx-maker-merck-and-co-drew-up-doctor-hit-list-the-australian/feed/ 0 A&A: Recurrence of Cardiotoxicity After Lipid Rescue from Bupivacaine-Induced Cardiac Arrest. http://www.raeducation.com/2009/04/aa-recurrence-of-cardiotoxicity-after-lipid-rescue-from-bupivacaine-induced-cardiac-arrest/ http://www.raeducation.com/2009/04/aa-recurrence-of-cardiotoxicity-after-lipid-rescue-from-bupivacaine-induced-cardiac-arrest/#comments Sat, 25 Apr 2009 18:39:06 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=379 Yet Another Related Posts Plugin.]]> With good reason, most regional anesthetic rooms and carts now come with a bag of intralipid. But is one bag enough? Perhaps not. Nice case report from Marwick et al.

Ovid: Recurrence of Cardiotoxicity After Lipid Rescue from Bupivacaine-Induced Cardiac Arrest..

No related posts.

Related posts brought to you by Yet Another Related Posts Plugin.

]]> http://www.raeducation.com/2009/04/aa-recurrence-of-cardiotoxicity-after-lipid-rescue-from-bupivacaine-induced-cardiac-arrest/feed/ 1 Acute compartment syndrome of the lower limb and the effect of postoperative analgesia on diagnosis http://www.raeducation.com/2009/04/acute-compartment-syndrome-of-the-lower-limb-and-the-effect-of-postoperative-analgesia-on-diagnosis/ http://www.raeducation.com/2009/04/acute-compartment-syndrome-of-the-lower-limb-and-the-effect-of-postoperative-analgesia-on-diagnosis/#comments Thu, 09 Apr 2009 13:00:39 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=226 Yet Another Related Posts Plugin.]]> Wow. A phenomenal review of analgesia in orthopedic trauma for any acute pain medicine consultant. Not only a quick review of the pathophysiology, but great review of cases in the literature.

Acute compartment syndrome of the lower limb and the effect of postoperative analgesia on diagnosis — Mar et al. 102 (1): 3 — British Journal of Anaesthesia.

No related posts.

Related posts brought to you by Yet Another Related Posts Plugin.

]]> http://www.raeducation.com/2009/04/acute-compartment-syndrome-of-the-lower-limb-and-the-effect-of-postoperative-analgesia-on-diagnosis/feed/ 0 Intra-articular bupivacaine: potentially chrondotoxic? http://www.raeducation.com/2009/03/intra-articular-bupivacaine-potentially-chrondotoxic/ http://www.raeducation.com/2009/03/intra-articular-bupivacaine-potentially-chrondotoxic/#comments Sat, 14 Mar 2009 13:00:28 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=353 Yet Another Related Posts Plugin.]]> A very nice editorial summarizing the state of the evidence for single-injection and continuous intra-articular infusions of local anesthetics. This has the potential to significantly change pain management strategies following joint surgery.

Intra-articular bupivacaine: potentially chrondotoxic?
S. T. Webb and S. Ghosh
British Journal of Anaesthesia 2009 102(4):439-441; doi:10.1093/bja/aep036

No related posts.

Related posts brought to you by Yet Another Related Posts Plugin.

]]> http://www.raeducation.com/2009/03/intra-articular-bupivacaine-potentially-chrondotoxic/feed/ 0 Review of Multimodal Analgesia Data http://www.raeducation.com/2009/03/review-of-multimodal-analgesia-data/ http://www.raeducation.com/2009/03/review-of-multimodal-analgesia-data/#comments Tue, 10 Mar 2009 23:27:13 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=323
  • What do you do when your block appears permanent? Alain Borgeat presents a fantastic case discussion reviewing the management...
    • Related posts brought to you by Yet Another Related Posts Plugin.]]>     Perhaps this offers a good opportunity to carefully review the evidence behind our common therapies. I think many of us will be quite interested in the upcoming editorials sure to emanate from A&A and Anesthesiology.

    Fraud Case Rocks Anesthesiology Community
    Mass. Researcher Implicated in Falsification of Data, Other Misdeeds
    Anesthesiology News
    Issue: March 2009, 35:3

    Related posts:

    1. What do you do when your block appears permanent? Alain Borgeat presents a fantastic case discussion reviewing the management...

    Related posts brought to you by Yet Another Related Posts Plugin.

    ]]>     http://www.raeducation.com/2009/03/review-of-multimodal-analgesia-data/feed/ 0     Buprenorphine added to the local anesthetic for brachial plexus block to provide postoperative analgesia in outpatients…[Reg Anesth Pain Med. 2001 Jul-Aug] – PubMed Result http://www.raeducation.com/2009/01/buprenorphine-added-to-the-local-anesthetic-for-brachial-plexus-block-to-provide-postoperative-analgesia-in-outpatientsreg-anesth-pain-med-2001-jul-aug-pubmed-result/ http://www.raeducation.com/2009/01/buprenorphine-added-to-the-local-anesthetic-for-brachial-plexus-block-to-provide-postoperative-analgesia-in-outpatientsreg-anesth-pain-med-2001-jul-aug-pubmed-result/#comments Thu, 15 Jan 2009 14:51:13 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=268 Yet Another Related Posts Plugin.]]> More data supporting buprenorphine as an adjunct in prolonging the analgesic effect of peripheral nerve block.

    Buprenorphine added to the local anesthetic for br…[Reg Anesth Pain Med. 2001 Jul-Aug] – PubMed Result
    .

    No related posts.

    Related posts brought to you by Yet Another Related Posts Plugin.

    ]]>     http://www.raeducation.com/2009/01/buprenorphine-added-to-the-local-anesthetic-for-brachial-plexus-block-to-provide-postoperative-analgesia-in-outpatientsreg-anesth-pain-med-2001-jul-aug-pubmed-result/feed/ 0     Buprenorphine added to the local anesthetic for axillary brachial plexus block prolongs postoperative analgesia http://www.raeducation.com/2009/01/buprenorphine-added-to-the-local-anesthetic-for-axillary-brachial-plexus-block-prolongs-postoperative-analgesia/ http://www.raeducation.com/2009/01/buprenorphine-added-to-the-local-anesthetic-for-axillary-brachial-plexus-block-prolongs-postoperative-analgesia/#comments Thu, 15 Jan 2009 14:48:49 +0000 admin https://www.anest.ufl.edu/gator-rap/?p=266 Yet Another Related Posts Plugin.]]> From RAPM, Volume 27, Issue 2, Pages 162-167 (March 2002)

     

    Very nice study with very significant results. This was a very significant increase in post-operative analgesia. 

    Buprenorphine added to the local anesthetic for axillary brachial plexus block prolongs postoperative analgesia.

    No related posts.

    Related posts brought to you by Yet Another Related Posts Plugin.

    ]]>     http://www.raeducation.com/2009/01/buprenorphine-added-to-the-local-anesthetic-for-axillary-brachial-plexus-block-prolongs-postoperative-analgesia/feed/ 2