The Effect of Perioperative IV Lidocaine on Post-Op Pain and Immune Function

What’s nice about this study is the control group: PCEA! The differences in pain scores were statistically different but of questionable clinical difference. Another study with incremental pain improvements, but importantly reflecting non-incremental changes in perioperative stress response. Also note the higher pain scores despite increased PCEA volume and intra-op opioid use (although, this could increase OR decrease post-op pain depending on your literature purview). A&A via Ovid.

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